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KMID : 0361020230660070485
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Korean Journal of Otolaryngology - Head and Neck Surgery
2023 Volume.66 No. 7 p.485 ~ p.488
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Inconsistent Polymerase Chain Reaction Test Results From the Upper And Lower Airways of a Patient Who Underwent Total Laryngectomy During the Incubation Period for Coronavirus Disease
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Lee Dong-Yun
Ban Myung-Jin
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Abstract
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On March 11, 2020, the World Health Organization declared coronavirus disease (COVID-19),an infection caused by SARS-CoV-2, a pandemic. There have been reports of differences in theresults of COVID-19 tests of patients who underwent total laryngectomy, depending on thesample collection site. The upper respiratory tract mucosa or saliva is the recommended sam-ple collection site for an initial diagnosis. However, in some patients who underwent total lar-yngectomy, only samples from the lower respiratory tract tested positive. We report the caseof a patient who was preoperatively infected with COVID-19. He underwent a total laryngec-tomy during the incubation period, and tested positive using a sample collected from the up-per respiratory tract. Of a total of six polymerase chain reaction tests performed using samplesfrom both the upper and lower respiratory tract, two had inconsistent results. The patient de-veloped COVID-19 pneumonia and was successfully managed with antiviral medication. Nopostoperative complications were observed.
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KEYWORD
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COVID-19, Laryngectomy, Polymerase chain reaction, Specimen collection
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